SCASSO ALEJANDRO FABIO,STEFANO FRANCISCO JOSÉ EVARISTO
申请号:
IN327/MUMNP/2014
公开号:
IN2014MN00327A
申请日:
2014.02.20
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The present invention pertains generally to the field of transdermal drug delivery. More specifically the invention relates to a device for the transdermal delivery of an alkaline pharmaceutically active compound that is susceptible to degradation in its free base form (e.g. rivastigmine) that comprises an adhesive matrix layer a backing layer and a release or protective layer wherein the adhesive matrix layer comprises said pharmaceutically active compound triethylcitrate and hydrochloric acid. The invention also relates to methods of preparing such devices.