JACOBY, DOUGLAS, B.,KESAVAN, KAMALA,SENTISSI, ABDELLAH,EGAN, E. MICHAEL
申请号:
EP08873442
公开号:
EP2282755A4
申请日:
2008.09.17
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention is directed to novel methods of inhibiting angiogenesis using chlorotoxin agents. In some embodiments, the inventive methods include intravenous, intraocular, intravitreal, subjunctival injection, and/or topical administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment and/or amelioration of ocular diseases characterized by neovascularization, such as wet macular degeneration. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.