John W. Crabb,Robert G. Salomon,Bela Anand-Apte,Quteba Ebrahem,Kutralanathan Renganathan
申请号:
US13369964
公开号:
US20120230996A1
申请日:
2012.02.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention pertains to methods of inhibiting angiogenesis (e.g., ocular angiogenesis choroidal neovasculariztion) in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of 5 oxidative peptide modification of polyunsaturated fatty acids (PUFA) in the individual, and administration of the agent inhibits angiogenesis in the individual.