Reis E. Sousa, Caetano,Pennington, Daniel,Schulz, Oliver,Joffre, Olivier Pierre,Sancho-Madrid, David,Rogers, Neil Charles
申请号：
AU2008278831
公开号：
AU2008278831B2
申请日:
2008.07.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The invention relates to the regulation of the immune system, and in particularto the finding that the CLEC9a molecule is a marker for dendritic cells which arecapable of cross-presenting extracellular antigens via the MHC class I pathway.This makes them particularly suitable for generation of cytotoxic T lymphocyteresponses. Materials and methods are provided both for the induction of immuneresponses against target antigens, and for the inhibition or suppression ofundesirable immune responses in which these cells are involved.
