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CONJUGUES POLYPEPTIDE-ANTIGENE AVEC DES ACIDES AMINES NON NATURELS
专利权人:
INC.;SUTROVAX
发明人:
FAIRMAN, JEFFERY,HEINRICHS, JON,CHAN, WEI
申请号:
CA3048981
公开号:
CA3048981A1
申请日:
2017.12.29
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Methods for the production of immunogenic compositions containing a non-natural amino acid are disclosed. The non-natural amino acid can be a site for attachment of antigens, such as bacterial capsular polysaccharides, to make immunogenic conjugates. Bio-orthogonal attachment chemistry incorporated into the non-natural amino acids allows for more efficient and potent antigen presentation to the immune system, simplified purification, and more well-defined structure of these semi-synthetic immunogens.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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