SUPPRESSOR DER EXPRESSION VON MCP-1 UND LINDERNDES MITTEL FÜR ENTZÜNDLICHE KRANKHEITEN, PHARMAZEUTIKUM, ERGÄNZUNGSSTOFF, NAHRUNGSMITTEL, GETRÄNK ODER NAHRUNGSMITTELZUSATZ, BEI DEM DER SUPPRESSOR VERWENDET WIRD
A suppressor of the expression of MCP-1 is provided that is excellent in safety and is widely applicable to, for example, foods. The suppressor of the expression of MCP-1 according to the present invention is characterized by containing auraptene. Auraptene is contained in citrus fruits such as Hassaku, Amanatsu, Natsumikan, and grapefruit. Since these citrus fruits have been eaten for a long time, the present invention has no problem in safety. Furthermore, even when added to, for example, foods, auraptene does not impair the flavor thereof because it is substantially tasteless and odorless. Since auraptene has a low calorific value, for example, an obese person or a diabetic patient can ingest it over a long period of time. Auraptene suppresses the expression of MCP-1 at a genetic level (see FIG. 1) and a protein level.
