VASIEVICH ELIZABETH ANN,CHEN WEIHSU,TONEY KENYA,CONN GREGORY,BEDU ADDO FRANK,HUANG LEAF
申请号：
IN7544/DELNP/2010
公开号：
IN2010DN07544A
申请日:
2010.10.26
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
A composition and method for activating immune cells ex-vivo, or inducing an immune response in a subject including a composition comprising at least one chiral cationic lipid. The chiral cationic lipid in one embodiment comprises a nonsteroidal cationic lipid having a structure represented by formula (I) wherein in Rl is a quaternary ammonium group, Y1 is a spacer chosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is a chiral carbon, R2 and R3 are independently chosen from a saturated fatty acid, an unsaturated fatty acid, an ester-linked hydrocarbon, phosphor-diesters, and combinations thereof
