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SELS D'ADDITION D'ACIDE D'UN INHIBITEUR DE TRANSFERT DE BRINS DE L'INTÉGRASE
专利权人:
Sandoz AG
发明人:
申请号:
EP18206725.6
公开号:
EP3653629A1
申请日:
2018.11.16
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to acid addition salts of the integrase strand transfer inhibitor bictegravir with acids selected from the group consisting of hydrochloric acid and 1,5 naphthalenedisulfonic acid and crystalline forms thereof. Furthermore, the invention relates to processes for the preparation of the salts and their respective crystalline forms and to a pharmaceutical composition comprising one or more of them, preferably in a predetermined and/or effective amount, at least one pharmaceutically acceptable excipient and optionally one ore more additional antiviral agent(s). The pharmaceutical composition of the present invention can be used as a medicament, in particular for the treatment and/or prophylaxis of HIV-1 infections.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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