An aqueous formulation of vitamins and the preparation method thereof. Based on the weight, the raw material composition of the aqueous formulation includes: liposomes, 1.89~5.85 parts vitamin A, 2~4 parts vitamin D, 1~3 parts vitamin E, 1~2 parts vitamin K, 4~6 parts vitamin B1, 2~4 parts vitamin B2, 2~6 parts vitamin B6, 1~2 parts vitamin B12, 1~6 parts vitamin C, 2~4 parts vitamin H, 1~2 parts folic acid, and solubilizers.