Joseph W. Franses,Elazer R. Edelman,Angelo Manuel De Almeida Cardoso,Helen Marie Nugent
申请号:
US14592395
公开号:
US20150196687A1
申请日:
2015.01.08
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to composition and a method of using the composition for modulting proliferation, invasiveness, the expression of a biomarker of an abnormal cell, of reducing the risk of patient cell becoming abnormal, or of modulating proliferation of a carcinoma-associated fibroblast or of a tumor-associated macrophage. The invention also relates to a method of culturing the composition to produce molecules that modulate abnormal cell proliferation, invasiveness, or metastasis. The composition comprises a biocompatible matrix and cells engrafted thereon.