#$%^&*AU2014204445A120140731.pdf#####H:\aar\Interwoven\NRPortbl\DCC\AAR\6458236 Ldoc-16/07/2014 ABSTRACT This disclosure relates generally to the field of anti-pathogenic agents, including a modified defensin molecule with anti-pathogen activity. Genetically modified plants and their progeny or parts expressing or containing the modified defensin and anti-pathogen compositions for use in horticulture and agriculture and as animal and human medicaments are also provided.