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Metal compounds mixed or sulphated, as phosphate binders
专利权人:
OPKO IRELAND GLOBAL HOLDINGS; LTD.
发明人:
Norman Bryson Roberts,Maurice Webb,Benjamin Joseph Rankin
申请号:
US14065162
公开号:
US09242869B2
申请日:
2013.10.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A mixed metal compound for pharmaceutical use is free from aluminum and has a phosphate binding capacity of at least 30%, by weight of the total weight of phosphate present, over a pH range of from 2-8. The compound is especially useful for treatment of hyperphosphataemia. The metals are preferably iron (III) and at least one of calcium, magnesium, lanthanum and cerium. A metal sulphate for pharmaceutical use is selected from at least one of calcium, lanthanum and cerium sulphate compounds and has a phosphate binding capacity of at least 30% by weight of the total phosphate present, over a pH range from 2-8.
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