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Metal compounds, mixed or sulphated, as phosphate binders
专利权人:
Benjamin J Rankin;Norman B Roberts;Maurice Webb
发明人:
Norman B Roberts,Maurice Webb,Benjamin J Rankin
申请号:
US12828462
公开号:
US08568792B2
申请日:
2010.07.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A mixed metal compound for pharmaceutical use is free from aluminium and has a phosphate binding capacity of at least 30%, by weight of the total weight of phosphate present, over a pH range of from 2-8. The compound is especially useful for treatment of hyperphosphataemia. The metals are preferably iron (III) and at least one of calcium, magnesium, lanthanum and cerium. A metal sulphate for pharmaceutical use is selected from at least one of calcium, lanthanum and cerium sulphate compounds and has a phosphate binding capacity of at least 30% by weight of the total phosphate present, over a pH range from 2-8.
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