The subject of present invention is related to a compound or the pharmaceutically acceptable salt thereof having excellent inhibition to DGAT and ingestion inhibition. The solution of present invention is to provide a compound represented by the general formula (I) or the pharmaceutically acceptable salt thereof: [in formula, R1 is hydrogen atom or carboxy group； R2 and R3 each independently represents C1-C6 alkyl group, or R2 and R3 are together with the carbon atom to which they bind to form C3-C6 cycloalkane optionally substituted by one carboxy group or carboxymethyl group； U is nitrogen atom and the like； V is nitrogen atom and the like； W is nitrogen atom and the like； Z is nitrogen atom and the like； R4’s each independently represents halogen atom or C1-C6 alkyl group； A is oxygen atom and the like； E is nitrogen atom and the like； J is nitrogen atom and the like； L is nitrogen atom and the like； M is nitrogen atom and the like； m is 0 or 1； n is an integer of 0-2].本發明之課題係關於具有優異的DGAT阻礙作用及攝食抑制作用的化合物或其藥理上可容許的鹽。本發明之解決手段係提供一種通式(I)所表示之化合物或其藥理上可容許的鹽：[式中，R1為氫原子或羧基；R2及R3獨立表示為C1-C6烷基，或R2及R3與結合的碳原子一起形成可經1個羧基或羧甲基取代的C3-C6環烷；U為氮原子等；V為氮原子等；W為氮原子等；Z為氮原子等；R4獨立為鹵素原子或C1-C6烷基；A為氧原子等；E為氮原子等；J為氮原子等；L為氮原子等；M為氮原子等；m為0或1；n為0至2之整數]。
