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Derivados de nip-tiazol como inhibidores de la 11-beta-hidroxiesteroide deshidrogenasa
- 专利权人:
- MERCK PATENT GMBH
- 发明人:
- LERICHE, CAROLINE,CARNIATO, DENIS,ROCHE, DIDIER,CHARON, CHRISTINE,DOARE, LILIANE
- 申请号：
- ES09741800
- 公开号：
- ES2432383T3
- 申请日:
- 2009.04.08
- 申请国别(地区):
- ES
- 年份:
- 2013
- 代理人:
- 摘要：
- Thiazole derivative selected from the group consisting of: a) 3,3-dimethyl-1- {4- [4- (octahydro-quinolin-1-carbonyl) -thiazol-2-yl] -piperidin-1-yl} - butan-1-one b) (octahydro-quinolin-1-yl) - {2- [1- (pyridin-3-carbonyl) -piperidin-4-yl] -thiazol-4-yl} -methanone c) cyclohexyl- cyclopropyl-amide 2- (1-cyclohexanecarbonyl-piperidin-4-yl) -thiazol-4-carboxylic d) cyclohexyl-cyclopropyl-amide 2- (1-cyclopentanecarbonyl-piperidin-4-yl) -thiazol-4 acid -carboxylic e) cyclohexyl-cyclopropyl-amide 2- (1-cyclobutanecarbonyl-piperidin-4-yl) -thiazol-4-carboxylic f) cyclohexyl-cyclopropyl-amide 2- (1-cyclopropanecarbonyl acid-piperidin-4- yl) -thiazol-4-carboxylic g) cyclohexyl-cyclopropyl-amide 2- [1- (3-cyclopentyl-propionyl) -piperidin-4-yl] -thiazol-4-carboxylic h) cyclohexyl-cyclopropyl-amide 2- [1- (2-ethyl-butyryl) -piperidin-4-yl] -thiazol-4-carboxylic acid i) cyclohexyl-cyclopropyl-amide 2- [1- (3,3-dimethyl-butyryl) acid - piperidin-4-yl] -thiazol-4-carboxylic acid j) cyclohexyl-cyclopropyl-amide 2- [1- (3-methyl-butyryl) -piperidin-4-yl] -thiazol-4-carboxylic k) cyclohexyl-cyclopropyl-amide 2- (1-isobutyryl acid piperidin-4-yl) -thiazol-4-carboxylic l) cyclohexyl-cyclopropyl-amide 2- (1-pentanoyl-piperidin-4-yl) -thiazol-4-acid carboxylic m) cyclohexyl-cyclopropyl--amide 2 - (1-propionyl-piperidin-4-yl) -thiazol-4-carboxylic n) cyclohexyl-cyclopropyl-amide 2- (1-acetyl-piperidin-4-yl) -thiazol-4-carboxylic acid o) cyclohexyl- cyclopropyl-amide 2- [1- (pyridin-3-carbonyl) -piperidin-4-yl] -thiazol-4-carboxylic acid p) cyclohexyl-cyclopropyl-amide 2- [1- (4-trifluoromethoxy-benzoyl ) -piperidin-4-yl] -thiazol-4-carboxylic q) [2- (1-cyclohexanecarbonyl-piperidin-4-yl) -thiazol-4-yl] - (octahydro-quinolin-1-yl) -methanone r ) [2- (1-cyclopentanecarbonyl-piperidin-4-yl) -thiazol-4-yl] - (octahydro-quinolin-1-yl) -methanone s) [2- (1-cyclobutanecarbonyl-piperidin-4-yl) -thiazol-4-yl] - (octahydro-quinolin-1-yl) -methanone t) [2- (1-cic lopropanocarbonil-piperidin-4-yl
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
