KIM, SUNG-EUN,LEE, SUNHO,RAJESH, RENGASAMY,KANG, DAE HO,RYU, HYUNG CHUL,KIM, JAE-SUN,LEE, SANGRYUL,KIM, KYONG CHEOL,RHO, JIN KYUNG,LEE, JAE CHEOL
申请号:
CA3083933
公开号:
CA3083933A1
申请日:
2018.12.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention provides a novel pyrimidine derivative compound and a salt thereof. The pyrimidine derivative compound effectively inhibits the growth of cancer cells in which c797s-mutated EGFR expression and MET amplification, which are major resistance mechanisms of third generation EGFR anticancer drugs, have occurred, thereby being effectively usable in the treatment of lung cancer.