Blood vessel organoid, methods of producing and using said organoids

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专利权人:

IMBA - Institut für Molekulare Biotechnologie GmbH

发明人:

Penninger, Josef,Wimmer, Reiner,Kerjaschki, Dontscho

申请号：

AU2018285579

公开号：

AU2018285579A1

申请日:

2018.06.15

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present invention relates to a method of generating an artificial blood vessel organoid, comprising providing stem cells capable of vascular differentiation, stimulating mesoderm differentiation in said stem cells, stimulating vascular differentiation in said stem cells, developing a cell aggregate from said stem cells, embedding said cell aggregates in a collagenous 3D matrix and stimulating vascular differentiation of the aggregate in said collagenous 3D matrix； organoids obtainable from said method, uses of said methods and organoids in manipulation and screening studied and kits for performing the methods.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/