The present invention discloses a class of water soluble taxane derivatives, a method for treating tumor using the same, use thereof as anti-tumor drugs and use thereof in the preparation of anti-tumor drugs. The water soluble taxane derivatives have the general formula (I-1), (I-2) or (I-3): wherein, R 1 is H or methyl； R 2 is H, methyl or acetyl； R 3 is phenyl or OC(CH 3 ) 3 ； X is H, C 1-6 alkyl or F； Y is F or C 1-6 alkyl substituted with one or more F； n is 1, 2, 3, 4, 5 or 6； W is NR 4 R 5 ·A or R 4 and R 5 are each independently H, C 1-6 alkyl optionally substituted with phenyl, or C 3-6 cycloalkyl； m is 0, 1, 2 or 3； and A is a pharmaceutically acceptable acid.
