ALVARO GIUSEPPE,DI FABIO ROMANO,TRANQUILLINI MARIA ELVIRA,SPADA SIMONE
申请号:
PL37353203
公开号:
PL211082B1
申请日:
2003.02.10
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
A composition comprising a compound of formula (I) wherein R represents halogen or C 1-4 alkyl ; R 1 represents C 1-4 alkyl; R 2 or R 3 independently represent hydrogen or C 1-4 alkyl; R 4 represents trifluoromethyl, C 1-4 alkyl, C 1-4 alkoxy, trifluoromethoxy or halogen; R 5 represents hydrogen , C 1-4 alkyl or C 3-7 cycloalkyl; R 6 is hydrogen and R 7 is a radical of formula (W): or R 6 is a radical of formula (W) and R 7 is hydrogen; X represents CH 2 , NR 5 or O; Y represents Nitrogen and Z is CH or Y represents CH and Z is Nitrogen; A represents C(O) or S(O)q, provided that when Y is nitrogen and Z is CH, A is not S(O)q; m is zero or an integer from 1 to 3; n is an integer from 1 to 3; p and q are independently an integer from 1 to 2; or pharmaceutically acceptable salts and solvates thereof and a selective serotonin reuptake inhibitor.