Timothy Colin Hancox;Stephen Price;Sukhjit Sohal;Neil Anthony Pegg;Stewart James Baker;Paul John Goldsmith;Stephen Joseph Shuttleworth
发明人:
Stewart James Baker,Paul John Goldsmith,Timothy Colin Hancox,Neil Anthony Pegg,Stephen Price,Stephen Joseph Shuttleworth,Sukhjit Sohal
申请号：
US12298507
公开号：
US08252792B2
申请日:
2007.04.25
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Thienopyrimidines of formula (Ia) or (Ib):wherein R1-R3 have any of the values described herein, and the pharmaceutically acceptable salt thereof have activity as inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase, in particular the p110 delta subtype, such as immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.
