SINGH, RAJINDER,SYLVAIN, CATHERINE,HOLLAND, SACHA,ZHANG, JING,PARTRIDGE, JOHN J.,CLOUGH, JEFFREY,ARGADE, ANKUSH
申请号:
CA2621503
公开号:
CA2621503C
申请日:
2006.09.07
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Triazole derivatives and pharmaceutical compositions containing thederivativesare disclosed as being useful in inhibiting the activity of the receptorprotein tyrosinekinase Axl. The triazole derivatives comprise a compound of formula (la) or(lb):(see formula Ia) (see formula Ib)wherein each of A, R1, R2, R3, R4 and R5 are defined as set out herein.Methods of usingthe derivatives in treating diseases or conditions associated with Axlcatalytic activity arealso disclosed.