Luke Green,Wolfgang Guba,Georg Jaeschke,Synese Jolidon,Lothar Lindemann,Antonio Ricci,Daniel Rueher,Heinz Stadler,Eric Vieira
申请号：
US14085064
公开号：
US09315498B2
申请日:
2013.11.20
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to ethynyl compounds of formula I-C1whereinR1, R2, R2′, R3, R3′, R6, U, V and W are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof, which are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
