Luke Green,Wolfgang Guba,Georg Jaeschke,Synese Jolidon,Lothar Lindemann,Antonio Ricci,Daniel Rueher,Heinz Stadler,Eric Vieira
申请号：
US13914336
公开号：
US08618296B2
申请日:
2013.06.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to ethynyl compounds of formula IwhereinR1, R2, R2′, R3, R3′, R4, R4′, U, V, W, Y, m, and n are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Compounds of formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
