Jiangsu Hengrui Medicine Co., Ltd.;Shanghai Hengrui Pharmaceutical Co., Ltd.
发明人:
申请号：
EP15868279.9
公开号：
EP3231802A4
申请日:
2015.11.10
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to pyridinecarboxamide derivatives, a preparation method thereof and a pharmaceutical use thereof. Specifically, the present invention relates to pyridinecarboxamide derivatives represented by general formula (I), wherein the substituents of the formula (I) are defined as the same as in the specification, a preparation method therefor, a pharmaceutical composition comprising the derivaties, and the uses as therapeutic agents, especially as inhibitors of the Renal Outer Medullary Potassium channel (ROMK) and in the preparation of medicaments for treating and/or preventing hypertension and heart failure.
