Embodiments of the present invention provide pharmaceutical compositions in unit dosage form that comprise a therapeutically effective amount of levothyroxine sodium an antioxidant in an amount sufficient to stabilize the levothyroxine sodium against oxidation an amount of an alditol sufficient to stabilize the levothyroxine sodium and at least two excipients selected from a filler, a binder, and a lubricant. Such compositions are free of added monosaccharide, disaccharide, and an oligosaccharide and are storage stable.
