A compound of formula (I) ** Formula ** in which ring B and the pyrimidine to which it is fused form a ring system selected from ** Formula ** * marks the point of attachment, R1 is hydrogen , 1-4C-alkyl (optionally substituted with halogen, hydroxy, amino, mono- or di-1-4Calkylamino), halogen, amino, -SR2, -SO-R2, SO2-R2, trifluoromethyl, cyano, 3-7C- cycloalkyl, 2-4C-alkenyl, 2- 4C-alkynyl, 1-4C-alkoxy (optionally substituted with halogen), 3-7C-cycloalkoxy, NR10R11, -C (O) NR12R13, - C (NH) NH2, -C (O) OR2, or a 5 or 6 membered monocyclic heteroarylene comprising 1 nitrogen atom and optionally 1, 2 or 3 additional heteroatoms independently selected from oxygen, nitrogen and sulfur, R2 is hydrogen, 1-4C-alkyl ( optionally substituted with halogen, hydroxy, amino, mono- or di-1-4Calkylamino) or 3-7C-cycloalkyl, R3 is hydrogen, 1-4C-alkyl or halogen, 1-4-C-alkoxy R4 is phenyl, thienyl, pyridinyl, thiazole ilo or oxazolyl and in which R4 is optionally independently substituted once or twice with R5A, R5A is 1-4C-alkyl, halogen or 1-4C-alkoxy or NR10R11, R5 is hydrogen, 1-4C-alkyl, halogen , 1-4C-alkoxy, NR10R11 or 3-7C-cycloalkyl, R6 is hydrogen or 1-4C-alkyl, R7 is -WY, W is a 5 or 6 membered monocyclic heteroarylene comprising 1 nitrogen atom and optionally 1, 2 or 3 additional heteroatoms independently selected from oxygen, nitrogen and sulfur or a bicyclic heteroarylene comprising 1 nitrogen atom and optionally 1, 2 or 3 additional heteroatoms independently selected from oxygen, nitrogen and sulfur and in which the heteroarylene 5 or 6-membered monocyclic and bicyclic heteroarylene are optionally substituted with R8, R8 is hydrogen, 1-4C-alkyl, 3-7C-cycloalkyl, 1-4C-haloalkyl, NR10R11, 1-4C-alkoxy, cyano, halogen or hydroxy, Y is hydrogen, aryl or a monocyclic heteroaryl 5 or 6 member ico comprising 1 nitrogen atom and optionally 1, 2 or 3 additional heteroatoms independently selected from oxygen, nitrogen, sulfur and in which the aryl or heteroaryl is optionally
