In fracture external force, fatigue, due to illness, and a method of manufacturing the substance to facilitate the repair of the fracture site, the food and drink of compounding the fracture repair accelerator, is to provide a fracture repair promoting products such as feed. Milk from which is obtained by elution with eluent of salt concentration 0.1M~1.0M fractions adsorb the basic protein by contacting the cation exchange resin material derived from milk or milk, adsorbed to the resin to produce a fracture repair promoter as an active ingredient a basic protein fraction.外力、疲労、病気による骨折において、骨折部位の修復を促進させる物質およびその製造方法、その骨折修復促進剤を配合する飲食品、飼料等の骨折修復促進製品を提供する。乳又は乳由来の原料を陽イオン交換樹脂に接触させて塩基性タンパク質を吸着させ、この樹脂に吸着した画分を塩濃度0.1M~1.0Mの溶出液で溶出して得られる乳由来塩基性タンパク質画分を有効成分として骨折修復促進剤を製造する。
