An adaptor and method for connecting a medical device to an endoscope are provided where the adaptor and the endoscope have non-compatible connectors. The adaptor includes a first portion including a proximal end portion having a mating connector for connecting to the elongate medical device and a distal end adapted to operably connect to an accessory channel of the endoscope. The first portion also includes a flange positioned distal to the mating connector and having a diameter greater than a diameter of the mating connector and a tubular body extending distally from the flange to the distal end, the tubular body being sized and shaped for insertion at least partially into the accessory channel. A lumen of the first portion extends through the first portion from the proximal end portion to the distal end where the lumen is adapted to receive a portion of the medical device therethrough.