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ORODISPERZIBILNA DOZNA JEDINICA KOJA SADRŽI ESTETROLSKU KOMPONENTU
专利权人:
Mithra Pharmaceuticals S.A.
发明人:
Jaspart, Séverine Francine Isabelle,Platteeuw, Johannes Jan,van den Heuvel, Denny Johan Marijn,Jaspart, SĂ©verine Francine Isabelle
申请号:
HRP20180889
公开号:
HRP20180889T1
申请日:
2018.06.06
申请国别(地区):
HR
年份:
2018
代理人:
摘要:
The invention provides an orodispersible solid pharmaceutical dosage unit having a weight between 30 and 1,000 mg, said dosage unit consisting of: €¢ 0.1-25 wt.% of estetrol particles containing at least 80 wt.% of an estetrol component selected from estetrol, estetrol esters and combinations thereof; and €¢ 75-99.9 wt.% of one or more pharmaceutically acceptable ingredients; the solid dosage unit comprising at least 100 µg of the estetrol component; and wherein the solid dosage unit can be obtained by a process that comprises compressing a dry blend of estetrol particles and one or more pharmaceutically acceptable excipients into a solid dosage unit. The solid dosage unit is easy to manufacture and perfectly suited for sublingual, buccal or sublabial administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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