MURTHY, NIREN,HERMANN, CHRISTOPHER,WILSON, DAVID SCOTT,NING, XINGHAI,BOYAN, BARBARA D.,SCHWARTZ, ZVI,GULDBERG, ROBERT,DIAB, TAMIM
申请号:
EP12757920
公开号:
EP2686018A4
申请日:
2012.03.19
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated.