Tamim Diab;Robert Guldberg;Christopher Hermann;David Scott Wilson;Barbara D. Boyan;Niren Murthy;Xinghai Ning;Zvi Schwartz
发明人:
Niren Murthy,Christopher Hermann,David Scott Wilson,Xinghai Ning,Barbara D. Boyan,Zvi Schwartz,Robert Guldberg,Tamim Diab
申请号:
US14005320
公开号:
US20140171367A1
申请日:
2012.03.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated.