Chu, Katherine A.,Chan, Elena T.,Fang, Ying,Jumaa, Mouhannad,Kirk, Christopher Justin,Muchamuel, Tony Marcel,Wang, Zhengping,Jiang, Jing,Jones, Jeffrey Joseph
申请号:
AU2013292636
公开号:
AU2013292636A1
申请日:
2013.07.17
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Liposomal compositions comprising peptide epoxyketone compounds are described, as well as methods of making and using such liposomal compositions. These liposomal compositions provide prolonged drug exposure (relative to non-liposomal compositions comprising peptide epoxyketone compounds) without significantly affecting biodistribution of the drug. Tolerability of peptide epoxyketone compounds was also enhanced when formulated in the liposomal compositions.