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Liposomal compositions of epoxyketone-based proteasome inhibitors
专利权人:
Inc.;Onyx Therapeutics
发明人:
Chu, Katherine A.,Chan, Elena T.,Fang, Ying,Jumaa, Mouhannad,Kirk, Christopher Justin,Muchamuel, Tony Marcel,Wang, Zhengping,Jiang, Jing,Jones, Jeffrey Joseph
申请号:
AU2013292636
公开号:
AU2013292636A1
申请日:
2013.07.17
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Liposomal compositions comprising peptide epoxyketone compounds are described, as well as methods of making and using such liposomal compositions. These liposomal compositions provide prolonged drug exposure (relative to non-liposomal compositions comprising peptide epoxyketone compounds) without significantly affecting biodistribution of the drug. Tolerability of peptide epoxyketone compounds was also enhanced when formulated in the liposomal compositions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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