CHAN KATRINA,LI LIANSHENG,ROMMEL CHRISTIAN,REN PINGDA,LIU YI,WILSON TROY EDWARD
申请号：
NZ61972710
公开号：
NZ619727A
申请日:
2010.07.15
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
A process for preparing a compound or a pharmaceutically acceptable salt thereof (such as duvelisib aka 8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one). such compounds being prepared from tetrahydropyran(THP) protected precursors. Said precursors being prepared by reacting a halo substituted 3-(1-aminoethyl)-2-phenylisoquinolin-1-one compound with a THP protected 6-chloropurine compound.
