GREENLEE MARK L U S A,WILKENING ROBERT U S A,APGAR JAMES U S A,SPERBECK DONALD U S A,WILDONGER KENNETH JAMES U S A,MENG DONGFANG U S A,PARKER DANN L JR U S A,MAMAI AHMED U S A
申请号:
IN404/KOLNP/2011
公开号:
IN299690B
申请日:
2009.08.10
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and method of using such compounds as antifungal agents and/or inhibitors of (l,3)-ß-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions. WO2010019206A1