APGAR JAMES,WILDONGER KENNETH JAMES,MENG DONGFANG,PARKER DANN L.,GREENLEE MARK L.,WILKENING ROBERT
申请号:
TN2011000050
公开号:
TN2011000050A1
申请日:
2011.01.28
申请国别(地区):
TN
年份:
2012
代理人:
摘要:
Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (l,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating, and/or preventing fungal infections and associated diseases and conditions.