HONG, SEUNG SUH,CHANG, SHIN JAE,KWON, KI SUNG,YI, KYE SOOK,KIM, SUNG HWAN,LEE, EUN BEOM,LEE, JAE WON,LEE, SO JUNG,SHIN, JI YOUNG,CHO, MYUNG SAM
申请号：
CA2902147
公开号：
CA2902147A1
申请日:
2014.03.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention provides a composition which comprises at least two influenza A virus-neutralizing-binding molecules binding an epitope within a stem region of a hemagglutinin (HA) protein of an influenza A virus, wherein the composition comprises: i) a first binding molecule which can neutralize at least one influenza A virus subtype which is selected from the group consisting of H1, H2, H5 and H9； ii) a second binding molecule which can neutralize at least one influenza A virus subtype which is selected from the group consisting of H1, H3, H5, H7 and H9. The mixed composition of the present invention effectively neutralizes both multiple influenza subtypes of phylogeny groups 1 and 2, and can be used jointly with chemical compounds, and thus is very effective in preventing and treating disease caused by an influenza virus.
