Britton Kenneth Corkey,Elfatih Elzein,Robert H. Jiang,Rao V. Kalla,Dmitry Koltun,Xiaofen Li,Ruben Martinez,Eric Q. Parkhill,Thao Perry,Jeff Zablocki,Chandrasekar Venkataramani,Michael Graupe,Juan Guer
申请号：
US14038646
公开号：
US09193694B2
申请日:
2013.09.26
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I:wherein Z1, Z2, Z3, Z4, X, Y, R2, R3 and R4 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
