The present invention provides a vaccine for preventing and/or treating Plasmodium falciparum infections, which comprises a polypeptide set forth in SEQ ID NO: 1 or represented by formula (1), and an adjuvant.X1-A-B-X2-Y-X3-(Y)n-X4-(Y)n-X5 (1)(In the formula, X1 represents the 1st to 7th amino acid residues in a polypeptide set forth in SEQ ID NO: 1； X2 represents the 73th to 177th amino acid residues； X3 represents the 178th to 258th amino acid residues； X4 represents the 259th to 289th amino acid residues； X5 represents the 290th to 334th amino acid residues； A represents an 8-mer repeat sequence contained in a 47-kd region of SERA polypeptide of Plasmodium falciparum； B represents a sequence of a serine-rich region contained in a 47-kd region of SERA polypeptide of Plasmodium falciparum； Y represents any one selected from A-A, A-B, and B； and n is an integer of 0 or 1).
