The present invention provides a vaccine for preventing and/or treating Plasmodium falciparum infections, which comprises a polypeptide set forth in SEQ ID NO: 1 or represented by formula (1), and an adjuvant. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒX 1 -A-B-X 2 -Y-X 3 -(Y)n-X 4 -(Y)n-X 5 €ƒ€ƒ€ƒ€ƒ€ƒ(1) (In the formula, X 1 represents the 1st to 7th amino acid residues in a polypeptide set forth in SEQ ID NO: 1 X 2 represents the 73th to 177th amino acid residues X 3 represents the 178th to 258th amino acid residues X 4 represents the 259th to 289th amino acid residues X 5 represents the 290th to 334th amino acid residues A represents an 8-mer repeat sequence contained in a 47-kd region of SERA polypeptide of Plasmodium falciparum B represents a sequence of a serine-rich region contained in a 47-kd region of SERA polypeptide of Plasmodium falciparum Y represents any one selected from A-A, A-B, and B and n is an integer of 0 or 1.)
