HANSEN JOSHUA,CORREA MATTHEW DANIEL,RAHEJA RAJ,LOPEZ GTRONA ANTONIA,MAN HON WAH,MULLER GEORGE W,KHALIL EHAB M,MACBETH KYLE,CATHERS BRIAN E,POURDEHNAD MICHAEL
申请号:
IN201747000977
公开号:
IN201747000977A
申请日:
2017.01.10
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
123Compounds of formula (I) for treating preventing or managing cancer are disclosed. Also disclosed are methods of treating preventing or managing cancer such as leukemia comprising administering the compounds. In certain embodiments the method of treatment comprise administering a compound provided herein in combination with a second agent. Pharmaceutical compositions and single unit dosage forms comprising the compounds are also disclosed. In Formula (I) R is optionally substituted cycloalkyi aryl heteroaryl or heterocyclyl and R and R are each halo.