Rudolf A. Baumgartner;Norman N. Kim;William K. McVicar;Thomas G. McCauley
发明人:
Norman N. Kim,William K. McVicar,Thomas G. McCauley,Rudolf A. Baumgartner
申请号：
US13004380
公开号：
US08877732B2
申请日:
2011.01.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor A1 agonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. In one embodiment, the prostaglandin analog is latanoprost and the adenosine receptor A1 agonist is Compound A, ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate, having the structure,
