NORMAN N. KIM,WILLIAM K. MCVICAR,THOMAS MCCAULEY,RUDOLF A. BAUMGARTNER
申请号：
PT11732309
公开号：
PT2523669T
申请日:
2011.01.11
申请国别(地区):
PT
年份:
2017
代理人:
摘要：
The present invention is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor A1 agonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. In one embodiment, the prostaglandin analog is latanoprost and the adenosine receptor A1 agonist is Compound A, ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate, having the structure,
