GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
AMANS, DOMINIQUE,ATKINSON, STEPHEN JOHN,BARKER, MICHAEL DAVID,CAMPBELL, MATTHEW,DIALLO, HAWA,DOUAULT, CLEMENT,GARTON, NEIL STUART,LIDDLE, JOHN,RENAUX, JESSICA FANNY,SHEPPARD, ROBERT JOHN,WALKER, ANN L
申请号:
CA2986199
公开号:
CA2986199A1
申请日:
2016.05.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Compounds of formula (I): wherein X, Y, R1 and R3-R11 are as herein defined, and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis.