Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" (RU)
发明人:
Заитов Леонид Махмутович (RU),Недосеев Сергей Леонидович (RU),Пальцев Михаил Александрович (RU),Созонтов Евгений Аркадьевич (RU)
申请号：
RU2012125306/14
公开号：
RU2012125306A
申请日:
2012.06.19
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. bioartificial system consisting of complex cell culture, placed on an implantable biocompatible carrier by volume, characterized in that it further comprises extracorporeally arranged tanks with a nutrient medium, connected to the internal volume nositelya.2. The system of claim 1, wherein the carrier is a layered composition comprising an inner core for accommodation of culture media, the separation membrane and the external matrix for placing the complex cellular kultur.3. A system according to claim 1 characterized in that the connection is made in the form of a tube introduced into the internal volume nositelya.4. A system according to claim 1 characterized in that the inner volume of the support is connected a drain pipe to the drain rezervuarom.5. A system according to claim 1 characterized in that the connection is made in the form of a tube, which is a flat coil embedded in nositel.6. The system according to claim 1, characterized in that the tube portion embedded in a carrier formed from a porous material allowing diffusion of nutrient medium permeability of molecules to the complex cellular kultur.7. The system according to claim 5, characterized in that the pitch of the helix is less than the characteristic diffusion length of the nutrient medium in the cell kulture.8 molecules. The system according to claim 1, characterized in that the number of tanks with a nutrient medium, connected to the carrier tubes, equal to the number of nutrient sred.9. System according to claims 1 and 2, characterized in that the support body has the form of a flat 1-5 mm thick and linear dimensions corresponding to the dimensions implantatsii.10 zone. System according to claims 1 and 2, characterized in that the carrier has the form of an axisymmetric1. Биоискусственная система, состоящая из комплекса клеточных культур, размещенных на имплантируемом объемном биосовместимом носителе, отличающаяся тем, что она дополнительно содержит экстракорпорально расположенные резервуар
