The present invention provides uses of plasminogen in preventing and/or treating osteoporosis and diseases related to the osteoporosis. The present invention also provides a drug and a product for preventing and/or treating osteoporosis.本發明涉及纖溶酶原用於預防和/或治療骨質疏鬆及其相關病症的用途。本發明還涉及預防和/或治療骨質疏鬆的藥物及製品。