In the antidepressant steroid compound and its production method and use, the structure of the compound is represented by the formula I, wherein the definition of each substituent is as described in the description and the claims. The compounds of the present invention are useful for the prevention, treatment, treatment or alleviation of many diseases, such as depression. Embedded image抗うつステロイド化合物およびその製造方法と使用で、当該化合物の構造は式Iで表され、ここで、各置換基の定義は明細書および請求の範囲に記載の通りである。本発明の化合物は、うつ病などの多くの疾患、病症の防止、処置、治療または軽減に有用である。【化1】