A Continuous Ambulatory Hemofilter includes an outer casing, multifunction pump, hemofilter, reverse osmosis filter, power source, drainage bag, blood lines and fluid lines, characterized in that the hemofiltrate from the hemofilter is moved to a reverse osmosis filter. The ultrafiltrate fluid from the reverse osmosis filter flows to the out-flow tube of the hemofilter vein line through a dedicated fluid line. The exit of the reverse osmosis filter is connected to a drainage bag. The multifunction pump moves blood from a permanent jugular catheter to the hemofilter, and fluids between the hemofilter, reverse osmosis filter, vein line and drainage bag. An electrode is placed at the in-flow tube of the hemofilter to measure incoming blood osmolality. The electrode is connected to a microprocessor that is further connected to a computer-controlled valve at the out-flow line of the reverse osmosis filter. The microprocessor is connected with a memory card.