J. Manuel Perez Figueroa,Oscar Santiesteban,Charalambos Kaittanis
申请号:
US14491374
公开号:
US20150087605A1
申请日:
2014.09.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are compositions and methods for treating anthrax, inhibiting anthrax toxins and inhibiting anthrax toxin-induced cytotoxicity. Carboxylic acid-containing small molecules can be used in the methods and compositions disclosed herein, for example, sulindac and derivatives thereof may be used. Methods of screening for carboxylic acid-containing small molecules that can be used to treat anthrax are disclosed. Targeting the anthrax toxin reduces the risks of anthrax spores.