The present invention provides compositions and methods for wound healing and scar reduction. The compositions and methods of the present invention comprise at least one EP4 agonist as described herein. Wounds and / or scars that can be treated by the compositions and methods of the present invention can result from events such as surgery, trauma, disease, mechanical injury, burns, radiation, poisoning, and the like.本発明は、創傷治癒及び瘢痕減少のための組成物及び方法を提供する。本発明の組成物及び方法は、本明細書に記載の少なくとも1つのEP4作動薬を含む。本発明の組成物及び方法によって治療することができる創傷及びまたは瘢痕は、手術、外傷、疾患、機械的損傷、熱傷、放射線、中毒等の事象から生じ得る。