THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MC GILL UNIVERSITY
发明人:
Trifiro Mark,Paliouras Miltiadis,Roche Philip,Dotan Idit,Beitel Lenore,Alvarado Carlos,Carnevale Matthew,Mitmaker Elliot Jonathan
申请号：
US201415036707
公开号：
US10124075(B2)
申请日:
2014.11.14
申请国别(地区):
美国
年份:
2018
代理人:
Merchant & Gould P.C.
摘要：
A bionanofluid includes a carbon-based nanomaterial substantially mono-dispersed in a fluid. The carbon-based nanomaterial is surface modified with a polar group when the fluid is polar or with a non-polar group when the fluid is non-polar, and functionalized with a biological targeting moiety to allow specific association of the carbon-based nanomaterial to a targeted entity. A hybrid bionanofluid includes the bionanofluid, with the carbon-based nanomaterial further modified with a hybrid nanoparticle which includes an alloy, transition metal, semi-conductor, semi-metal or polymer based nanoparticle with biological targeting moiety. A hydrogel, foam, cream, spray or dried product includes the bionanofluid or hybrid bionanofluid. The bionanofluid or hybrid bionanofluid are useful in multimodal imaging (photo-luminescence, luminescence, photo-acoustic, MRI, ultrasound) and/or cellular targeting.
